Research program

on organs- and organoids-on-chip

Driven by

Funded by

Operated by

The exploratory research program Organs and organoids on chips (PEPR MED-OOC) aims to deploy a new generation of biological models in France through the development of organs and organoids on chips (O&OoC). The State has entrusted its management to the CEA, the CNRS and Inserm, and the scientific direction to Xavier Gidrol (CEA), Anne-Marie Gué (CNRS), and Jean Rosenbaum (Inserm). MED-OOC is funded by France 2030 over 6 years and has a budget of €48.4 million operated by the National Research Agency (ANR).

Type 1 Diabetes on chip (MAGIC)

Development of vascularized pancreatic islets on a chip to monitor immune response and graft survival in patients with type 1 diabetes after transplantation.

Tumor-on-a-chip to improve patient care (TME On Chip)

Patient-derived tumor-on-a-chip modeling to predict efficacy and identify optimal personalized treatment by faithfully recapitulating patient pathology.

Multi-organ coupling on a chip for metabolic syndrome monitoring (MSY-OOC)

Development of a new generation of human liver-on-a-chip to model liver dysfunctions in metabolic syndrome and interactions between involved organs.

Technology for microenvironment engineering and imaging for organs-on-a-chip (EnVie)

Modular and standardized reconstruction of organs on a chip, integrating microenvironment engineering and 3D imaging to reproduce their architecture and main functions.

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