
Research program
on organs- and organoids-on-chip
The exploratory research program Organs and organoids on chips (PEPR MED-OOC) aims to deploy a new generation of biological models in France through the development of organs and organoids on chips (O&OoC). The State has entrusted its management to the CEA, the CNRS and Inserm, and the scientific direction to Xavier Gidrol (CEA), Anne-Marie Gué (CNRS), and Jean Rosenbaum (Inserm). MED-OOC is funded by France 2030 over 6 years and has a budget of €48.4 million operated by the National Research Agency (ANR).

Type 1 Diabetes on chip (MAGIC)
Development of vascularized pancreatic islets on a chip to monitor immune response and graft survival in patients with type 1 diabetes after transplantation.

Tumor-on-a-chip to improve patient care (TME On Chip)
Patient-derived tumor-on-a-chip modeling to predict efficacy and identify optimal personalized treatment by faithfully recapitulating patient pathology.

Multi-organ coupling on a chip for metabolic syndrome monitoring (MSY-OOC)
Development of a new generation of human liver-on-a-chip to model liver dysfunctions in metabolic syndrome and interactions between involved organs.

Technology for microenvironment engineering and imaging for organs-on-a-chip (EnVie)
Modular and standardized reconstruction of organs on a chip, integrating microenvironment engineering and 3D imaging to reproduce their architecture and main functions.
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2025 Call winners
Awardees The winners of the ANR 2025 call for projects are expected to…
9 October 2025

Episode 1 – Organs on chip
Two months ago, in Grenoble, the MED-OOC PEPR was inaugurated, a France2030 research program focusing on organs and organoids on chips.
🧪 This first episode is dedicated to organs-on-chips (OOC): miniature devices capable of reproducing certain functions of a human organ. They pave the way for more accurate and ethical biomedical research, serving the medicine of tomorrow.
9 October 2025

FC3R Webinaire
December 12, 2024 – Emily Tubbs presents her advances in pancreatic modeling with a view to personalized medicine for type 1 diabetes. Maria-Carla Parrini introduces you to tumor-on-a-chip technology, or ToC, and its implications for the personalized medicine of tomorrow.
9 October 2025
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